Analytical Applications in Drug Discovery

Tuesdays, 15:15-17 h, starting Feb. 22 and ending on April 12, 2022. Since Zoom functionality is limited, I plan to bring the lesson – typically the first hour – on Twitch and the exercises – typically after the lesson – on Zoom. 

About the lecture

SS22 VV#50310-01

A course based on the bachelor analytical cycle (ending with Analytik VI) for students that plan or do master or PhD studies requiring instrumental analysis (HPLC, LC-MS etc). It will be more interactive than the bachelor lecture. The second hour of the lessons will be used for exercises. The results will serve as basis for the pass/fail decision.

Book the course if you can imagine to – or already do – work in analytical labs or on a PhD thesis with practical analytical aspects – and if you liked the style of Analytik VI. 

Do not book the course if you are looking for a cheap credit point. Engagement is required!

Educational objective

Insight to analytical practise in research: You know material and information sources and providers, you learn to search, manage and extract literature on practical examples and derive proposals for starting method development. You use Excel for the evaluation of typical amounts of data and do some troubleshooting. You learn more on advanced instrumental analytics, especially about HPLC and mass spectrometry.

Contents (subject to change):

  • Introduction and toolbox: What to find where. Suppliers, literature, information, software. Registrations, software installation
  • Method development 
  • Quantification case study
  • Biomarker case study
  • High Resolution Mass spectrometry
  • Advanced HPLC
  • Advanced Mass Spectrometry

Administrative

Credits will be granted according to your perfomance in the exercises/quizzes. These will be done typically within the second hour of the lessons. You need a laptop with MS office software, internet access, SciFinder access and previous registration on this webpage.  Contact stephan.mueller@unibas.ch in case of problems. 

Links

2022 Dates and times

Course dates are Tuesdays, 15:15-17 h, starting Feb. 22 and ending on April 12, 2022.